LongevityMap variant
Entry Details
- Longevity Association
- Non-significant
- Population
- Irish
- Study Design
- 100 control samples (59% female and 41% male) and 93 aged consecutive samples (70% female, 30% male with an age range of 80-97 years) were analyzed for Intron I microsatellite repeats
- Conclusions
- No significant differences were observed between centenarians and controls
- Identifier
- IFNG
- Cytogenetic Location
- 12q15
- UCSC Genome Browser
- View 12q15 on the UCSC genome browser
Gene details
- HGNC symbol
- IFNG
- Aliases
- IFG; IFI
- Common name
- interferon gamma
- Description
- This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
- Other longevity studies of this gene
- 5
- OMIM
- 147570
- Ensembl
- ENSG00000111537
- UniProt/Swiss-Prot
- IFNG_HUMAN
- Entrez Gene
- 3458
- UniGene
- 856
- HapMap
- View on HapMap
Homologs in model organisms
In other databases
- CellAge
- This gene is present as IFNG