LongevityMap variant
Entry Details
- Longevity Association
- Significant
- Population
- Ashkenazi Jewish
- Study Design
- Case-control study for phenotype and genotype of exceptional longevity in a genetically homogenous population (Ashkenazi Jews, 80% female), and their offspring (320 subjects, 55% female). An age-matched control group of Ashkenazi Jews (n = 258) was used as control group.
- Conclusions
- A functional CETP variant contributed to the better health performance and thus exceptional longevity (P < 0.05).
- Identifier
- CETP
- In Other Studies (IDs)
- 95
- Cytogenetic Location
- 16q13
- UCSC Genome Browser
- View 16q13 on the UCSC genome browser
Gene details
- HGNC symbol
- CETP
- Aliases
- BPIFF; HDLCQ10
- Common name
- cholesteryl ester transfer protein
- Description
- The protein encoded by this gene is found in plasma, where it is involved in the transfer of cholesteryl ester from high density lipoprotein (HDL) to other lipoproteins. Defects in this gene are a cause of hyperalphalipoproteinemia 1 (HALP1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
- Other longevity studies of this gene
- 17
- OMIM
- 118470
- Ensembl
- ENSG00000087237
- UniProt/Swiss-Prot
- A0A0S2Z3F6_HUMAN
- Entrez Gene
- 1071
- UniGene
- 89538
- HapMap
- View on HapMap
Homologs in model organisms
- Danio rerio
- cetp
In other databases
- GenAge human genes
- This gene is present as CETP