LongevityMap variant group
Entry Details
- Longevity Association
- Non-significant
- Population
- American of Japanese origin
- Study Design
- Total mortality, cause-specific mortality, and healthy survival were evaluated for associations with CETP genetic variants common in 3562 Japanese-American men from Honolulu Heart Program
- Conclusions
- No association was found between rs2303790 and mortality (p =.38). There was a trend for lower mortality for men with the Int 14A variant in rs5742907, though it failed to reach statistical significance.
Variants (2)
1.
- Identifier
- rs5742907
- Cytogenetic Location
- 16q13
- UCSC Genome Browser
- View 16q13 on the UCSC genome browser
2.
- Identifier
- rs2303790
- Cytogenetic Location
- 16q13
- UCSC Genome Browser
- View 16q13 on the UCSC genome browser
Gene details
- HGNC symbol
- CETP
- Aliases
- BPIFF; HDLCQ10
- Common name
- cholesteryl ester transfer protein
- Description
- The protein encoded by this gene is found in plasma, where it is involved in the transfer of cholesteryl ester from high density lipoprotein (HDL) to other lipoproteins. Defects in this gene are a cause of hyperalphalipoproteinemia 1 (HALP1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
- Other longevity studies of this gene
- 17
- OMIM
- 118470
- Ensembl
- ENSG00000087237
- UniProt/Swiss-Prot
- A0A0S2Z3F6_HUMAN
- Entrez Gene
- 1071
- UniGene
- 89538
- HapMap
- View on HapMap
Homologs in model organisms
- Danio rerio
- cetp
In other databases
- GenAge human genes
- This gene is present as CETP