GenAge entry for HBP1 (Homo sapiens)
Gene name (HAGRID: 196)
- HGNC symbol
- HBP1
- Aliases
- Common name
- HMG-box transcription factor 1
Potential relevance to the human ageing process
- Main reason for selection
- Entry selected based on evidence showing that the gene product to be a target of genes previously linked to ageing
- Description
HBP1 has been related to DNA unwinding and stress response [860]. In mice, HBP1 and other HMG chromosomal proteins have been shown to suffer alterations at various levels during ageing [791], but HBP1 has not been directly related to human ageing.
Cytogenetic information
- Cytogenetic band
- 7q22-q31
- Location
- 107,169,015 bp to 107,202,529 bp
- Orientation
- Plus strand
Protein information
- Gene Ontology
-
Process: GO:0006351; transcription, DNA-templated
GO:0006355; regulation of transcription, DNA-templated
GO:0007050; cell cycle arrest
GO:0016055; Wnt signaling pathway
Cellular component: GO:0005654; nucleoplasm
Show all GO termsFunction: GO:0003677; DNA binding
GO:0003723; RNA binding
GO:0005515; protein binding
Protein interactions and network
- Protein-protein interacting partners in GenAge
- MYC, CREBBP, EP300, RB1, HDAC1, SIN3A, ESR1
- STRING interaction network
Retrieve sequences for HBP1
Homologs in model organisms
In other databases
- CellAge
- This gene is present as HBP1