Schizosaccharomyces pombe GenDR Dietary Restriction Gene Manipulation: GIT3

Gene Information (Entrez Gene ID: 2538770)

Symbol
GIT3
Name
G-protein coupled receptor Git3
Organism
Schizosaccharomyces pombe (AnAge)
Entrez Gene ID
2538770

Potential relevance to dietary restriction and ageing

Observations

GIT3 encodes a G protein-coupled receptor for glucose. Git3 deletion increases chronological lifespan in conditions where glucose consumption is not affected. Constitutive activation of Galpha subunit acting downstream of Git3 accelerates aging and inhibits effect of DR [2562].

References

    Homologs

    No homologs found

    External links

    Entrez Gene
    ID 2538770
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