Disclaimers, Credits, and Copyright

By using this site, its content, information, and software you agree to assume all risks associated with your use or transfer of information and/or software. The Human Ageing Genomic Resources (HAGR) come without warranty of any kind. We, HAGR's coordinators and curators, do not warrant that the site will operate correctly or that the site or its server are free of computer viruses or other harmful devices. You agree to hold HAGR's coordinators and curators harmless from any claims relating to the use of this site.

In no event shall we be liable for any use of the HAGR website, its databases, software, or information derived thereof. For documents and software available from HAGR, we do not assume any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed. Regarding the software, we are not responsible for any damage its use may cause. Use at your own risk. Although copyrighted, you may distribute ARCT according to the same conditions of the GNU public licence.

Although we provide information on certain diseases, the information included in HAGR does not serve as medical advice. If you believe you or someone you know suffer from one of such diseases you should contact a qualified physician. We accept no responsibility or liability for any loss, cost, claim or expense arising from any reliance on such content or information.

We do not support any commercial products in HAGR and there is no publicity listed in HAGR. All links and references are made based on merit. We are not responsible for these links and do not assume any responsibility for the accuracy or functioning of these. References to products or publications do not imply endorsement of that product or publication.

Most content in HAGR is in the public domain. The HAGR design and layout, including graphics such as icons and logos, its software, the data sheets in its databases, including the observations in AnAge and descriptions in GenAge, and the HAGR interface are copyrighted. Copyright © 2002 - 2020 by João Pedro de Magalhães. Some rights are reserved, as detailed in the Creative Commons License. senescence.info is copyrighted and some rights are also reserved, as detailed elsewhere.

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 Unported License.

In brief, HAGR is free for all purposes, including commercial, educational, and research purposes, provided you mention the use of HAGR in subsequent presentations, publications, etc. Although referring the URL might be enough in some cases (e.g., teaching and websites), for scientific publications we ask that you cite HAGR using:

Tacutu, R., Thornton, D., Johnson, E., Budovsky, A., Barardo, D., Craig, T., Diana, E., Lehmann, G., Toren, D., Wang, J., Fraifeld, V. E., de Magalhaes, J. P. (2018) "Human Ageing Genomic Resources: new and updated databases." Nucleic Acids Research 46(D1):D1083-D1090.

The above paper refers to all databases and tools in HAGR and please use it to cite any HAGR content, with a few exceptions of specific databases, as follows. For works that only employ the molecular signatures of ageing, please cite:

de Magalhaes, J. P., Curado, J., Church, G. M. (2009) "Meta-analysis of age-related gene expression profiles identifies common signatures of aging." Bioinformatics 25(7):875-881.

If you employ GenDR, please cite:

Wuttke, D., Connor, R., Vora, C., Craig, T., Li, Y., Wood, S., Vasieva, O., Shmookler Reis, R., Tang, F., de Magalhaes, J. P. (2012) "Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes." PLoS Genetics 8(8):e1002834.

If you are only using the molecular signatures of DR, please cite:

Plank, M., Wuttke, D., van Dam, S., Clarke, S., de Magalhaes, J. P. (2012) "A meta-analysis of caloric restriction gene expression profiles to infer common signatures and regulatory mechanisms." Molecular BioSystems 8(4):1339-1349.

For works only employing the LongevityMap, please cite:

Budovsky, A., Craig, T., Wang, J., Tacutu, R., Csordas, A., Lourenco, J., Fraifeld, V. E., de Magalhaes, J. P. (2013) "LongevityMap: A database of human genetic variants associated with longevity." Trends in Genetics 29:559-560.

If you use DrugAge, please cite:

Barardo, D., Thornton, D., Thoppil, H., Walsh, M., Sharifi, S., Ferreira, S., Anzic, A., Fernandes, M., Monteiro, P., Grum, T., Cordeiro, R., De-Souza, E.A., Budovsky, A., Araujo, N., Gruber, J., Petrascheck, M., Fraifeld, V.E., Zhavoronkov, A., Moskalev, A., de Magalhaes, J.P. (2017) "The DrugAge database of ageing-related drugs." Aging Cell 16(3):594-597.

Lastly, if you employ CellAge, please cite:

Avelar, R. A., Ortega, J. G., Tacutu, R., Tyler, E. J., Bennett, D., Binetti, P., Budovsky, A., Chatsirisupachai, K., Johnson, E., Murray, A., Shields, S., Tejada-Martinez, D., Thornton, D., Fraifeld, V. E., Bishop, C. L., & de Magalhaes, J. P. (2020) "A multidimensional systems biology analysis of cellular senescence in aging and disease." Genome Biology 21(1):91.

If you only use the gene expression signature of cellular senescence, please cite:

Chatsirisupachai, K., Palmer, D., Ferreira, S., & de Magalhaes, J. P. (2019) "A human tissue-specific transcriptomic analysis reveals a complex relationship between aging, cancer, and cellular senescence." Aging Cell 18(6):e13041.

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You may link freely to our databases. If you wish to generate multiple queries or retrieve large amounts of data, please contact us in advance to avoid a server overload. Failure to do so or misuse of HAGR by, for example, hacking or generating spam will result in your IP being blocked. Please visit our download guidelines.

Usage of HAGR or any of its associated resources implies that you have read, understood, and accepted these terms and conditions and will abide by them. Please visit this page often as our terms and conditions may change without prior notice.