GenDR Dietary Restriction Gene Manipulation: Ilp2
Gene Information (Entrez Gene ID: 39150)
- Symbol
- Ilp2
- Aliases
- CG8167 dilp Dilp DILP Dilp 2 dilp-2 dILP-2 Dilp-2 dilp2 dIlp2 dILP2 Dilp2 DILP2 Dmel\CG8167 Ilp Ilp-2 ilp2 ILP2 IRP
- Name
- Insulin-like peptide 2
- Organism
- Drosophila melanogaster (AnAge)
- Entrez Gene ID
- 39150
Potential relevance to dietary restriction and ageing
- Observations
-
Ilp2 is down-regulated in long-lived mutants. Ilp2 null mutants are significantly longer-lived with a 8-13% longer median lifespan, but have a normal DR response. Ilp2 Ilp3 Ilp5 triple null mutants fail to have a normal response to DR. Their response is right shifted, with mutants shorter-lived compared to wild-type on low but longer-lived on high yeast concentrations [2580].
- References
-
In other databases
- GenAge model organism genes
- This gene is present as Ilp2
Homologs
No homologs found
External links
- FlyBase
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- Ensembl
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- Entrez Gene
- ID 39150
- Homologues
- Search HomoloGene
- UniProt
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- Internet
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