GenDR Dietary Restriction Gene Manipulation: Ilp5
Gene Information (Entrez Gene ID: 2768992)
- Symbol
- Ilp5
- Aliases
- CG33273 dilp Dilp DILP Dilp 5 dilp-5 dILP-5 Dilp-5 dilp5 dIlp5 dILP5 Dilp5 DILP5 Dmel\CG33273 Ilp Ilp-5 ilp5 ILP5
- Name
- Insulin-like peptide 5
- Organism
- Drosophila melanogaster (AnAge)
- Entrez Gene ID
- 2768992
Potential relevance to dietary restriction and ageing
- Observations
-
Abundance of Ilp5 mRNA is reduced under DR. Ilp5 null mutants have a normal lifespan under ad libitum and a normal DR response. Ilp2 Ilp3 Ilp5 triple null mutants fail to have a normal response to DR. Their response is right shifted, with mutants being shorter-lived compared to wild-type on low but longer-lived on high yeast concentrations [2580].
- References
-
Homologs
- Danio rerio
- ins
External links
- FlyBase
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- Entrez Gene
- ID 2768992
- Homologues
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- Internet
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