GenDR Dietary Restriction Gene Manipulation: Cbs
Gene Information (Entrez Gene ID: 33081)
- Symbol
- Cbs
- Aliases
- CBS CG1753 dCBS Dmel\CG1753
- Name
- Cystathionine beta-synthase
- Organism
- Drosophila melanogaster (AnAge)
- Entrez Gene ID
- 33081
Potential relevance to dietary restriction and ageing
- Observations
-
Ubiquitous or neuron-specific overexpression of Cbs enhances longevity in fully-fed animals. Cbs RNAi partly abrogates increased lifespan by DR, but has no effect on fully fed animals. It appears that Cbs upregulation is required for increased lifespan under low-nutrient conditions. Response of male flies to DR is muted in comparison with females [2589].
- References
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In other databases
- GenAge model organism genes
- CellAge
- A homolog of this gene for Homo sapiens is present as CBS
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as CBS
Homologs
- Caenorhabditis elegans
- cysl-4
- Danio rerio
- cbsa
- Homo sapiens
- CBS
- Mus musculus
- Cbs
- Rattus norvegicus
- Cbs
- Saccharomyces cerevisiae
- CYS4
- Schizosaccharomyces pombe
- cys12
External links
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- ID 33081
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar