Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: SFA1

Gene Information (Entrez Gene ID: 851386)

Symbol
SFA1
Aliases
ADH5
Name
Sensitive to FormAldehyde 1
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
851386

Potential relevance to dietary restriction and ageing

Observations

sfa1;yhb1 double mutant cancels out the ability of moderate DR to extend replicative lifespan, but not chronological lifespan. Deleting YHB1 partially abolishes the DR-induced replicative lifespan extension, whereas deleting SFA1 alone had no effect. Yhb1 and Sfa1 may play redundant roles [2581].

References

    Homologs

    Caenorhabditis elegans
    CELE_Y50D4C.2
    Danio rerio
    zgc:77938
    Drosophila melanogaster
    Fdh
    Homo sapiens
    ADH5
    Mus musculus
    Adh5
    Rattus norvegicus
    Adh1
    Schizosaccharomyces pombe
    SPCC13B11.04c

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 851386
    Homologues
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    UniProt
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    Internet
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