GenDR Dietary Restriction Gene Manipulation: CG4389
Gene Information (Entrez Gene ID: 34276)
- Symbol
- CG4389
- Aliases
- BcDNA:GH12558 CG 4389 CG4389 Dmel\CG4389
- Name
- CG4389 gene product from transcript CG4389-RA
- Organism
- Drosophila melanogaster (AnAge)
- Entrez Gene ID
- 34276
Potential relevance to dietary restriction and ageing
- Observations
-
Muscle-specific RNAi knockdown of CG489 which reduces its mRNA levels by 25-35%, significantly reduces the DR-dependent lifespan extension. CG4389 RNAi animals exhibit only 20% increase while controls display a lifespan increase of 123% upon DR [2597].
- References
-
Homologs
- Caenorhabditis elegans
- ech-1
- Danio rerio
- hadhab
- Homo sapiens
- HADHA
- Mus musculus
- Hadha
- Rattus norvegicus
- Hadha
External links
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- ID 34276
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar