GenDR Dietary Restriction Gene Manipulation: NDE2
Gene Information (Entrez Gene ID: 851474)
- Symbol
- NDE2
- Aliases
- NDH2
- Name
- NADH Dehydrogenase, External 2
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 851474
Potential relevance to dietary restriction and ageing
- Observations
-
Overexpression of NDE1 and NDE2 increases intracellular NAD/NADH ratio by lowering NADH concentration and increases replicative lifespan by 20-25%. This lifespan extension is non-additive with 0.5% glucose restriction [2329].
- References
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In other databases
- GenAge model organism genes
- This gene is present as NDE2
Homologs
- Schizosaccharomyces pombe
- SPAC3A11.07
External links
- Saccharomyces Genome Database
- Search
- Ensembl
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- Entrez Gene
- ID 851474
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar