GenDR Dietary Restriction Gene Manipulation: ATG8
Gene Information (Entrez Gene ID: 852200)
- Symbol
- ATG8
- Aliases
- APG8 AUT7 CVT5
- Name
- ubiquitin-like protein ATG8
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 852200
Potential relevance to dietary restriction and ageing
- Observations
-
Methionine restriction (a form of dietary restriction), aquired through MET2 or MET17 knockout, enhances lifespan in yeast. In both MET2 and MET17 models, this lifespan extension is abolished by the deletion of ATG5, ATG7, or ATG8 lifespan reaching comparable or even lower survival levels to those of controls.
- References
-
In other databases
- GenAge model organism genes
Homologs
- Caenorhabditis elegans
- lgg-1
- Danio rerio
- zgc:92606
- Drosophila melanogaster
- Atg8b
- Homo sapiens
- GABARAPL3
- Mus musculus
- Gabarap
- Rattus norvegicus
- Gabarap
- Schizosaccharomyces pombe
- atg8
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- ID 852200
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar