GenDR Dietary Restriction Gene Manipulation: ISW2
Gene Information (Entrez Gene ID: 854480)
Potential relevance to dietary restriction and ageing
- Observations
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Under normal conditions, deletion of ISW2 in yeast extends replicative lifespan by 24%. Lifespan is also extended by limiting glucose concentrations in the diet to either 0.5% or 0.05%, however, these CR conditions are not able to extend lifespan when ISW2 is deleted, instead shortening lifespan.
- References
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In other databases
- GenAge model organism genes
- This gene is present as ISW2
Homologs
- Caenorhabditis elegans
- isw-1
External links
- Saccharomyces Genome Database
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- Ensembl
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- Entrez Gene
- ID 854480
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar