Caenorhabditis elegans GenDR Dietary Restriction Gene Manipulation: cbs-1

Gene Information (Entrez Gene ID: 181215)

Symbol
cbs-1
Name
Cystathionine Beta-Synthase
Organism
Caenorhabditis elegans (AnAge)
Entrez Gene ID
181215

Potential relevance to dietary restriction and ageing

Observations

Overexpression of CBS-1 significantly extends median (but not maximal) lifespan of wild-type N2 worms, while RNA interference of CBS-1 has no effect on longevity. Contrastly, RNA interference of CBS-1 significantly decreases lifespan extension in the eat-2 dietary restriction model.

References

    In other databases

    GenAge model organism genes
    • This gene is present as cbs-1

    Homologs

    Danio rerio
    cbsb

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    ID 181215
    Homologues
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    UniProt
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    Internet
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