GenDR Dietary Restriction Gene Manipulation: kgb-1
Gene Information (Entrez Gene ID: 176866)
Potential relevance to dietary restriction and ageing
- Observations
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Loss-of-function kgb-1 mutant or inhibition of kgb-1 by post-developmental RNA interference reduces the lifespan extension of intermitent fasting. In the wild-type N2 worms, intermitent fasting increases lifespan by ~77%, while in the kgb-1 mutants lifespan extension is reduced to 23-24%.
- References
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Homologs
No homologs found
External links
- WormBase
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- Ensembl
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- Entrez Gene
- ID 176866
- Homologues
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- UniProt
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- Internet
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