GenDR Dietary Restriction Gene Manipulation: mek-1
Gene Information (Entrez Gene ID: 181004)
- Symbol
- mek-1
- Name
- MAP kinase kinase or Erk Kinase
- Organism
- Caenorhabditis elegans (AnAge)
- Entrez Gene ID
- 181004
Potential relevance to dietary restriction and ageing
- Observations
-
Loss-of-function mek-1 mutant reduces the lifespan extension of intermitent fasting. In the wild-type N2 worms, intermitent fasting increases lifespan by ~77%, while in the mek-1 mutants lifespan extension is reduced to ~22%.
- References
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In other databases
- CellAge
- A homolog of this gene for Homo sapiens is present as MAP2K7
Homologs
External links
- WormBase
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- Ensembl
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- Entrez Gene
- ID 181004
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar