GenDR Dietary Restriction Gene Manipulation: gas-1
Gene Information (Entrez Gene ID: 181646)
- Symbol
- gas-1
- Name
- Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
- Organism
- Caenorhabditis elegans (AnAge)
- Entrez Gene ID
- 181646
Potential relevance to dietary restriction and ageing
- Observations
-
Under normal conditions downregulation of gas-1 in worms increased mean lifespan by 16%. When worms lacking gas-1 were subjected to dietary restriction the difference in lifespan extension was reduced compared to the control (30% compared to 51% for the control). Thus downregulation of gas-1 triggers a dietary restriction like effect.
- References
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In other databases
- GenAge model organism genes
- This gene is present as gas-1
Homologs
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- ID 181646
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar