GenDR Dietary Restriction Gene Manipulation: CDC25
Gene Information (Entrez Gene ID: 851019)
- Symbol
- CDC25
- Aliases
- CTN1
- Name
- Cell Division Cycle 25
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 851019
Potential relevance to dietary restriction and ageing
- Observations
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The CDC25-10 allele extends mean and maximum replicative lifespan by 34% and 18%, respectively, at 30 degree Celsius. cdc25-10 mutants have an extended replicative lifespan under ad libitum. Growth on 0.5% glucose restriction does not further extend replicative lifespan of cdc25-10 mutants. CDC25 null mutant is not viable. CDC25 appears to act in the same genetic pathway as SIR2 and NPT1 and is suggested to be a genetic model of DR [2260].
- References
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In other databases
- GenAge model organism genes
- This gene is present as CDC25
Homologs
No homologs found
External links
- Saccharomyces Genome Database
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- Ensembl
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- Entrez Gene
- ID 851019
- Homologues
- Search HomoloGene
- UniProt
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- Internet
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