Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: ALG12

Gene Information (Entrez Gene ID: 855764)

Symbol
ALG12
Aliases
ECM39
Name
dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
855764

Potential relevance to dietary restriction and ageing

Observations

Yeast cells were subjected to dietary restriction (0.05% glucose compared to 2% glucose as a control). Deletion of ALG12 resulted in a 15% decrease in mean replicative lifespan compared to the control.

References

    In other databases

    GenAge model organism genes
    • This gene is present as ALG12

    Homologs

    Caenorhabditis elegans
    ZC513.5
    Danio rerio
    alg12
    Drosophila melanogaster
    CG8412
    Homo sapiens
    ALG12
    Mus musculus
    Alg12
    Rattus norvegicus
    Alg12
    Schizosaccharomyces pombe
    alg12

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 855764
    Homologues
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    UniProt
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    Internet
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