Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: ALG12

Gene Information (Entrez Gene ID: 855764)

Symbol
ALG12
Aliases
ECM39
Name
dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
855764

Potential relevance to dietary restriction and ageing

Observations

Yeast cells were subjected to dietary restriction (0.05% glucose compared to 2% glucose as a control). Deletion of ALG12 resulted in a 15% decrease in mean replicative lifespan compared to the control.

References
  • [4424] Schleit et al. (2013) "Molecular mechanisms underlying genotype-dependent responses to dietary restriction." Aging Cell 12(6):1050-1061 (PubMed)

In other databases

GenAge model organism genes
  • This gene is present as ALG12

Homologs

Caenorhabditis elegans
ZC513.5
Danio rerio
alg12
Drosophila melanogaster
CG8412
Homo sapiens
ALG12
Mus musculus
Alg12
Rattus norvegicus
Alg12
Schizosaccharomyces pombe
alg12

External links

Saccharomyces Genome Database
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Ensembl
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Entrez Gene
ID 855764
Homologues
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UniProt
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Internet
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