Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: AFG3

Gene Information (Entrez Gene ID: 856737)

Symbol
AFG3
Aliases
YTA10
Name
AAA family ATPase AFG3
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
856737

Potential relevance to dietary restriction and ageing

Observations

Yeast cells were subjected to dietary restriction (0.05% glucose compared to 2% glucose as a control). Deletion of AFG3 resulted in a 17% decrease in mean replicative lifespan compared to the control.

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as spg-7
    • This gene is present as AFG3

    Homologs

    Caenorhabditis elegans
    spg-7
    Danio rerio
    uncharacterized_E7F6
    Drosophila melanogaster
    CG6512
    Homo sapiens
    AFG3L2
    Mus musculus
    Afg3l1
    Rattus norvegicus
    Afg3l1

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 856737
    Homologues
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    UniProt
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    Internet
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