Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: GPR1

Gene Information (Entrez Gene ID: 851527)

Symbol
GPR1
Name
G-Protein coupled Receptor 1
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
851527

Potential relevance to dietary restriction and ageing

Observations

Deletion of GRP1 increases mean and maximum replicative lifespan by 41% and 26%, respectively. GRP1 deletion mutants have also longer chronological lifespan. Deletion of GPR1 extends replicative lifespan by reducing cAMP-PKA activity and provides a genetic model for DR [2260].

References

    In other databases

    GenAge model organism genes
    • This gene is present as GPR1

    Homologs

    No homologs found

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 851527
    Homologues
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    UniProt
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    Internet
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