GenDR Dietary Restriction Gene Manipulation: HST1
Gene Information (Entrez Gene ID: 854086)
- Symbol
- HST1
- Name
- Homolog of SIR Two (SIR2) 1
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 854086
Potential relevance to dietary restriction and ageing
- Observations
-
Deletion of HST1 blocks the residual replicative lifespan extension by hxk2 mutant in a sir2;fob1;hst2 triple mutant background [2309]. However, DR can increases the replicative lifespan to a similar extent in sir2;fob1;hst1;hst2 quadruple mutant cells as in sir2;fob1 double mutant cells under 0.5, 0.05 and 0.005% glucose conditions and even by hxk2 deletion mutant [2558].
- References
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In other databases
- GenAge model organism genes
- This gene is present as HST1
Homologs
- Danio rerio
- zgc:103539
- Mus musculus
- Sirt4
- Rattus norvegicus
- Sirt5
- Schizosaccharomyces pombe
- sir2
External links
- Saccharomyces Genome Database
- Search
- Ensembl
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- Entrez Gene
- ID 854086
- Homologues
- Search HomoloGene
- UniProt
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- Internet
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