GenDR Dietary Restriction Gene Manipulation: GSH1
Gene Information (Entrez Gene ID: 853344)
- Symbol
- GSH1
- Name
- glutathione (GSH) 1
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 853344
Potential relevance to dietary restriction and ageing
- Observations
-
Deletion of GSH1 confers deficiency in glutathione biosynthesis and further increases chronological lifespan under 0.5% glucose restriction, but does not extend chronological lifespan under 2% glucose. Therefore, GSH1 has a positive interaction with DR [2560].
- References
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In other databases
- GenAge model organism genes
- A homolog of this gene for Drosophila melanogaster is present as Gclc
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as GCLC
- LongevityMap
- A homolog of this gene for Homo sapiens is present as GCLC
Homologs
- Caenorhabditis elegans
- gcs-1
- Danio rerio
- gclc
- Drosophila melanogaster
- Gclc
- Homo sapiens
- GCLC
- Mus musculus
- Gclc
- Rattus norvegicus
- Gclc
- Schizosaccharomyces pombe
- gcs1
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- ID 853344
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar