GenDR Dietary Restriction Gene Manipulation: ERG5
Gene Information (Entrez Gene ID: 855029)
- Symbol
- ERG5
- Aliases
- CYP61
- Name
- ERGosterol biosynthesis 5
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 855029
Potential relevance to dietary restriction and ageing
- Observations
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Deletion of ERG5 decreases replicative lifespan by 35% in the a strain [2504], but increases mean chronological lifespan by 26 - 116% (26, 40, 43, 62, 116) in diploid cells [2593]. Deletion of ERG5 cancels out the replicative lifespan extension of 0.5% glucose restriction [2514].
- References
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In other databases
- GenAge model organism genes
- This gene is present as ERG5
- GenDR gene expression
- A homolog of this gene for Mus musculus is present as Cyp2j6
Homologs
- Drosophila melanogaster
- Cyp316a1
- Mus musculus
- Cyp2j6
- Rattus norvegicus
- Tbxas1
- Schizosaccharomyces pombe
- erg5
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- ID 855029
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar