Schizosaccharomyces pombe GenDR Dietary Restriction Gene Manipulation: pka1

Gene Information (Entrez Gene ID: 2539781)

Symbol
pka1
Aliases
git6 tpk
Name
cAMP-dependent protein kinase 1
Organism
Schizosaccharomyces pombe (AnAge)
Entrez Gene ID
2539781

Potential relevance to dietary restriction and ageing

Observations

pka1 knockouts exhibits a three-fold increase in chronological lifespan with up to 187% longer maximum lifespan [2342]. While deleting pka1 extends chronological lifespan under normal condition, there is no additive effect with DR [2563].

References

    In other databases

    GenAge model organism genes
    • This gene is present as pka1
    • A homolog of this gene for Saccharomyces cerevisiae is present as TPK3

    Homologs

    Caenorhabditis elegans
    kin-1
    Danio rerio
    prkx
    Drosophila melanogaster
    Pka-C3
    Mus musculus
    Prkx
    Rattus norvegicus
    Prkaca
    Saccharomyces cerevisiae
    TPK3

    External links

    Entrez Gene
    ID 2539781
    Homologues
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    UniProt
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    Internet
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