GenDR Dietary Restriction Gene Manipulation: atf1
Gene Information (Entrez Gene ID: 2540329)
- Symbol
- atf1
- Aliases
- gad7 mts1 sss1
- Name
- activating transcription factor 1
- Organism
- Schizosaccharomyces pombe (AnAge)
- Entrez Gene ID
- 2540329
Potential relevance to dietary restriction and ageing
- Observations
-
Activation of transcription factor Atf1 by Sty1 is required for chronological lifespan extension and enhanced heat stress resistance by DR. Deleting atf1 cancels out DR-mediated chronological lifespan extension and enhanced heat stress resistance. Overexpressing atf1 is not sufficient to promote chronological lifespan extension in cells lacking sty1 [2563].
- References
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In other databases
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as SKO1
Homologs
External links
- Entrez Gene
- ID 2540329
- Homologues
- Search HomoloGene
- UniProt
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- Internet
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