GenDR Dietary Restriction Gene Manipulation: drr-1
Gene Information (Entrez Gene ID: 174994)
- Symbol
- drr-1
- Name
- Dietary Restriction Response (WT but not eat-2 lifespan increased) 1
- Organism
- Caenorhabditis elegans (AnAge)
- Entrez Gene ID
- 174994
Potential relevance to dietary restriction and ageing
- Observations
-
drr-1 RNAi significantly extends mean lifespan of wild-type by 37 - 44%, but does not extend significantly the lifespan of eat-2 mutants. drr-1 RNAi does not affect pumping, but similar to DR reduces and delays reproduction as well as causes a slender appearance. drr-1 mRNA is 2-fold downregulated in response to DR [2240].
- References
-
In other databases
- GenAge model organism genes
- This gene is present as drr-1
Homologs
No homologs found
External links
- WormBase
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- Ensembl
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- Entrez Gene
- ID 174994
- Homologues
- Search HomoloGene
- UniProt
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- Internet
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