GenDR Dietary Restriction Gene Manipulation: let-363
Gene Information (Entrez Gene ID: 172167)
Potential relevance to dietary restriction and ageing
- Observations
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let-363 RNAi significantly extends the lifespan of wild-type, but does not further extend the long lifespan of eat-2 mutant [2312]. let-363 RNAi led to an average increase in lifespan of 8% in wild-type and 3% in eat-2 background, suggesting let-363 works synergistically with eat-2 mutation [2494]. Another study showed that DR fails to significantly extend lifespan of let-363 RNAi-treated animals [2566].
- References
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In other databases
- GenAge model organism genes
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as MTOR
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as TOR1
- LongevityMap
- A homolog of this gene for Homo sapiens is present as MTOR
- CellAge
- A homolog of this gene for Homo sapiens is present as MTOR
Homologs
- Danio rerio
- mtor
- Drosophila melanogaster
- Tor
- Homo sapiens
- MTOR
- Mus musculus
- Mtor
- Rattus norvegicus
- Mtor
- Saccharomyces cerevisiae
- TOR1
- Schizosaccharomyces pombe
- tor1
External links
- WormBase
- Search
- Ensembl
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- Entrez Gene
- ID 172167
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar