Caenorhabditis elegans GenDR Dietary Restriction Gene Manipulation: rheb-1

Gene Information (Entrez Gene ID: 176327)

Symbol
rheb-1
Name
RHEB (Ras Homolog Enriched in Brain) hom
Organism
Caenorhabditis elegans (AnAge)
Entrez Gene ID
176327

Potential relevance to dietary restriction and ageing

Observations

rheb-1 RNAi extends lifespan by mimicking the DR effect. Under ad lib conditions, rheb-1 RNAi extends lifespan by 19.1% and the longevity-promoting effects of two DR regimens solid DR and intermittent fasting are abolished [2566].

References

    In other databases

    GenAge model organism genes
    • This gene is present as rheb-1

    Homologs

    Danio rerio
    rhebl1
    Drosophila melanogaster
    Rheb
    Homo sapiens
    RHEBL1
    Mus musculus
    Rhebl1
    Rattus norvegicus
    Rhebl1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    ID 176327
    Homologues
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    UniProt
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    Internet
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