Caenorhabditis elegans GenDR Dietary Restriction Gene Manipulation: cbp-1

Gene Information (Entrez Gene ID: 176380)

Symbol
cbp-1
Name
CBP/p300 homolog 1
Organism
Caenorhabditis elegans (AnAge)
Entrez Gene ID
176380

Potential relevance to dietary restriction and ageing

Observations

Bacterial dilution DR induces cbp-1 expression. Overexpression of cbp-1 does not significantly affect lifespan. cbp-1 RNAi specifically in adults completely blocks lifespan extension by three distinct protocols of DR, partly by daf-2 mutation but not of cold and blocks the delay of other age-related pathologies by bacterial dilution DR [2569].

References

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as CREBBP

    Homologs

    Danio rerio
    uncharacterized_F1QC
    Drosophila melanogaster
    nej
    Homo sapiens
    CREBBP
    Mus musculus
    Ep300
    Rattus norvegicus
    Crebbp

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    ID 176380
    Homologues
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    UniProt
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    Internet
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