Caenorhabditis elegans GenDR Dietary Restriction Gene Manipulation: cbp-1

Gene Information (Entrez Gene ID: 176380)

Symbol
cbp-1
Name
CBP/p300 homolog 1
Organism
Caenorhabditis elegans (AnAge)
Entrez Gene ID
176380

Potential relevance to dietary restriction and ageing

Observations

Bacterial dilution DR induces cbp-1 expression. Overexpression of cbp-1 does not significantly affect lifespan. cbp-1 RNAi specifically in adults completely blocks lifespan extension by three distinct protocols of DR, partly by daf-2 mutation but not of cold and blocks the delay of other age-related pathologies by bacterial dilution DR [2569].

References
  • [2569] Zhang et al. (2009) "Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling." PLoS Biol. 7(11):e1000245 (PubMed)

In other databases

GenAge human genes
  • A homolog of this gene for Homo sapiens is present as CREBBP

Homologs

Danio rerio
uncharacterized_F1QC
Drosophila melanogaster
nej
Homo sapiens
CREBBP
Mus musculus
Ep300
Rattus norvegicus
Crebbp

External links

WormBase
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Ensembl
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Entrez Gene
ID 176380
Homologues
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Internet
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