LongevityMap variant
Entry Details
- Longevity Association
- Non-significant
- Population
- English (Oxford)
- Study Design
- 11 SNPs in the MTTP gene were genotyped in 1451 old people (mean age: 77.9 ± 0.2 years) and 777 controls (30- 50 years, mean age: 40.6 ± 0.2 years) to study association with longevity
- Conclusions
- MTTP gene variants were not significant association with longevity
- Identifier
- rs1800591
- In Other Studies (IDs)
- 430 2085
- Cytogenetic Location
- 4q23
- UCSC Genome Browser
- View 4q23 on the UCSC genome browser
Gene details
- HGNC symbol
- MTTP
- Aliases
- ABL; MTP
- Common name
- microsomal triglyceride transfer protein
- Description
- MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia. [provided by RefSeq, Jul 2008]
- Other longevity studies of this gene
- 20
- OMIM
- 157147
- Ensembl
- ENSG00000138823
- UniProt/Swiss-Prot
- B7Z7X3_HUMAN
- Entrez Gene
- 4547
- UniGene
- 195799
- HapMap
- View on HapMap