Filamentous fungus (Podospora anserina) longevity, ageing, and life history

Classification (HAGRID: 04244)

Taxonomy: Kingdom: Fungi
    Phylum: Ascomycota
        Class: Sordariomycetes
            Order: Sordariales
                Family: Lasiosphaeriaceae
                    Genus: Podospora
Species: Podospora anserina
Common name: Filamentous fungus

Maximum longevity: Not yet established
Observations: Ageing in these organisms is associated with the accumulation of defective mitochondrial DNA [0768]. Lifespan can be measured as the time it takes for cultures to stop growing. One mutant reportedly grew for over 12 years without signs of ageing [0769]. One study identified several pathways affected during ageing. Transcripts linked to ribosomes and proteasome quality control decreased. Transcript profiles associated with autophagy increased. Those associated with energy metabolism fluctuated [1203].

: No information is available on life history. Please contact us if you wish to suggest or contribute data.

No information on metabolism is available.

[1203] Philipp et al. (2013), A genome-wide longitudinal transcriptome analysis of the aging model Podospora anserina (PubMed)
[0921] van Diepeningen et al. (2010), Calorie restriction causes healthy life span extension in the filamentous fungus Podospora anserina (PubMed)
[0771] Osiewacz (2002), Genes, mitochondria and aging in filamentous fungi (PubMed)
[0769] Borghouts et al. (2001), Copper-modulated gene expression and senescence in the filamentous fungus Podospora anserina (PubMed)
[0767] Dufour et al. (2000), A causal link between respiration and senescence in Podospora anserina (PubMed)
[0770] Hermanns et al. (1994), Evidence for a life span-prolonging effect of a linear plasmid in a longevity mutant of Podospora anserina (PubMed)
[0768] Griffiths (1992), Fungal senescence (PubMed)