Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: MSN4

Gene Information (Entrez Gene ID: 853803)

Symbol
MSN4
Name
Multicopy suppressor of SNF1 mutation 4
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
853803

Potential relevance to dietary restriction and ageing

Observations

Deletion of MSN2 and MSN4 extends replicative lifespan [2559]. Deletion of MSN2 and MSN4 does not significantly decrease chronological lifespan under ad libitum, but attenuates chronological lifespan extension by water starvation and 0.5% glucose restriction [2556]. msn2 msn4 has no effect on replicative lifespan in PSY316, and does not prevent lifespan extension by DR [2260].

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as klf-1
    GenDR gene manipulations
    • A homolog of this gene for Caenorhabditis elegans is present as klf-1

    Homologs

    Caenorhabditis elegans
    klf-1
    Danio rerio
    sp7
    Homo sapiens
    SP5
    Mus musculus
    Sp5

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 853803
    Homologues
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    UniProt
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    Internet
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