GenDR Dietary Restriction Gene Manipulation: ATG5
Gene Information (Entrez Gene ID: 855954)
Potential relevance to dietary restriction and ageing
- Observations
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Methionine restriction (a form of dietary restriction), aquired through MET2 or MET17 knockout, enhances lifespan in yeast. In both MET2 and MET17 models, this lifespan extension is abolished by the deletion of ATG5, ATG7, or ATG8 lifespan reaching comparable or even lower survival levels to those of controls.
- References
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In other databases
- GenAge model organism genes
- CellAge
- A homolog of this gene for Homo sapiens is present as ATG5
Homologs
- Danio rerio
- atg5
- Drosophila melanogaster
- Atg5
- Homo sapiens
- ATG5
- Mus musculus
- Atg5
- Rattus norvegicus
- Atg5
- Schizosaccharomyces pombe
- atg5
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- ID 855954
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar