Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: GPA2

Gene Information (Entrez Gene ID: 856741)

Symbol
GPA2
Aliases
SSP101
Name
G Protein Alpha subunit 2
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
856741

Potential relevance to dietary restriction and ageing

Observations

Deletion of GPA2 increases mean and maximum replicative lifespan by 40% and 26%, respectively. Deletion of GPA2 extends replicative lifespan by reducing cAMP-PKA activity and provides a genetic model for DR [2260].

References

    In other databases

    GenAge model organism genes
    • This gene is present as GPA2
    GenDR gene manipulations
    • A homolog of this gene for Schizosaccharomyces pombe is present as gpa2

    Homologs

    Schizosaccharomyces pombe
    gpa2

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 856741
    Homologues
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    UniProt
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    Internet
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