GenDR Dietary Restriction Gene Manipulation: RPD3
Gene Information (Entrez Gene ID: 855386)
- Symbol
- RPD3
- Aliases
- MOF6 REC3 SDI2 SDS6
- Name
- Reduced Potassium Dependency 3
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 855386
Potential relevance to dietary restriction and ageing
- Observations
-
Deletion of the histone deacetylase gene RPD3 extends lifespan by 41%, independently of an intact Sir silencing complex (in the short-lived YSK661 strain) [203]. Deletion of RPD3 extends replicative lifespan and there was no additive effect by neither 0.1% glucose nor amino acid restriction [2552].
- References
-
In other databases
- GenAge model organism genes
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as HDAC1
- GenDR gene manipulations
- A homolog of this gene for Drosophila melanogaster is present as Rpd3
- CellAge
- A homolog of this gene for Homo sapiens is present as HDAC1
Homologs
- Caenorhabditis elegans
- hda-3
- Danio rerio
- hdac1
- Drosophila melanogaster
- Rpd3
- Homo sapiens
- HDAC1
- Mus musculus
- Gm10093
- Rattus norvegicus
- Hdac1l
- Schizosaccharomyces pombe
- clr6
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- ID 855386
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar