Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: IRE1

Gene Information (Entrez Gene ID: 856478)

Symbol
IRE1
Aliases
ERN1
Name
bifunctional endoribonuclease/protein kinase IRE1
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
856478

Potential relevance to dietary restriction and ageing

Observations

Yeast cells were subjected to dietary restriction (0.05% glucose compared to 2% glucose as a control). Deletion of IRE1 resulted in a 11% decrease in mean replicative lifespan compared to the control.

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as ire-1
    • A homolog of this gene for Drosophila melanogaster is present as Ire1
    GenDR gene manipulations
    • A homolog of this gene for Drosophila melanogaster is present as Ire1
    • A homolog of this gene for Caenorhabditis elegans is present as ire-1

    Homologs

    Caenorhabditis elegans
    ire-1
    Danio rerio
    ern2
    Drosophila melanogaster
    Ire1
    Homo sapiens
    ERN2
    Mus musculus
    Ern2
    Rattus norvegicus
    Ern2
    Schizosaccharomyces pombe
    ppk4

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 856478
    Homologues
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    UniProt
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    Internet
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