Caenorhabditis elegans GenDR Dietary Restriction Gene Manipulation: ire-1

Gene Information (Entrez Gene ID: 174305)

Symbol
ire-1
Name
IRE1 kinase related 1
Organism
Caenorhabditis elegans (AnAge)
Entrez Gene ID
174305

Potential relevance to dietary restriction and ageing

Observations

ire-1 mutation reduces slightly the lifespan under ad lib, but reduces significantly the lifespan extension by DR. ire-1 mutant has a significantly reduced slope in mean lifespan versus food concentrations relative to wild-type [2571].

References

    In other databases

    GenAge model organism genes
    • This gene is present as ire-1
    • A homolog of this gene for Drosophila melanogaster is present as Ire1
    GenDR gene manipulations
    • A homolog of this gene for Drosophila melanogaster is present as Ire1
    • A homolog of this gene for Saccharomyces cerevisiae is present as IRE1

    Homologs

    Danio rerio
    ern2
    Drosophila melanogaster
    Ire1
    Homo sapiens
    ERN2
    Mus musculus
    Ern2
    Rattus norvegicus
    Ern2
    Saccharomyces cerevisiae
    IRE1
    Schizosaccharomyces pombe
    ppk4

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    ID 174305
    Homologues
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    UniProt
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    Internet
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