Cell Senescence Entries for BAZ1A
- Cell Types
- Lung cancer, Osteosarcoma, Umbilical vein endothelial
- Cell Lines
- A549, HUVEC, U2OS
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Li et al. (2019) Chromatin remodeling factor BAZ1A regulates cellular senescence in both cancer and normal cells. Life Sci 229(2)225-232 (PubMed)
BAZ1A Gene Information
- HGNC symbol
- BAZ1A
- Aliases
- ACF1; hACF1; WALp1; WCRF180
- Common name
- bromodomain adjacent to zinc finger domain 1A
- Entrez Id
- 11177
- Description
- The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 [PubMed 20033039]).[supplied by OMIM, Apr 2010].
BAZ1A Ontologies
- Gene Ontology
-
Process: GO:6338; chromatin remodeling
GO:6261; DNA-dependent DNA replication
GO:6357; regulation of transcription by RNA polymerase II
GO:6275; regulation of DNA replication
GO:6334; nucleosome assembly
GO:16584; nucleosome positioning
GO:42766; nucleosome mobilization
GO:45740; positive regulation of DNA replication
Cellular component: GO:5634; nucleus
GO:16590; ACF complex
GO:8623; CHRAC
GO:228; nuclear chromosome
GO:5721; pericentric heterochromatin
Show all GO termsFunction: GO:46872; metal ion binding
GO:5515; protein binding
Homologs of BAZ1A in Model Organisms
- Caenorhabditis elegans
- athp-2
- Drosophila melanogaster
- Acf1
- Mus musculus
- Baz1a
- Rattus norvegicus
- Baz1a
- Saccharomyces cerevisiae
- YPL216W
In other databases
- CellAge gene expression
- This gene is present as BAZ1A
External links
- OMIM
- 605680
- Ensembl
- ENSG00000198604
- Entrez Gene
- 11177
- UniGene
- 509140
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- BAZ1A
- GeneCards
- BAZ1A