Cell Senescence Entries for BLVRA
- Cell Types
- Fibroblast
- Cell Lines
- Primary cell
- Cancer Cell?
- No
- Method
- Knockdown
- Type of senescence
- Stress-induced
- Senescence Effect
- Inhibits
- Primary Reference
- Kim et al. (2011) Biliverdin reductase A in the prevention of cellular senescence against oxidative stress. Exp Mol Med 43(1)15-23 (PubMed)
BLVRA Gene Information
- HGNC symbol
- BLVRA
- Aliases
- BLVR
- Common name
- biliverdin reductase A
- Entrez Id
- 644
- Description
- The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011].
BLVRA Ontologies
- Gene Ontology
-
Process: GO:42167; heme catabolic process
Cellular component: GO:5737; cytoplasm
GO:5829; cytosol
GO:70062; extracellular exosome
Show all GO termsFunction: GO:8270; zinc ion binding
GO:46872; metal ion binding
GO:16491; oxidoreductase activity
GO:5515; protein binding
GO:166; nucleotide binding
GO:4074; biliverdin reductase (NAD(P)+) activity
GO:106276; biliberdin reductase NAD+ activity
GO:106277; biliverdin reductase (NADP+) activity
Homologs of BLVRA in Model Organisms
External links
- OMIM
- 109750
- Ensembl
- ENSG00000106605
- Entrez Gene
- 644
- UniGene
- 488143
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- BLVRA
- GeneCards
- BLVRA