Cell Senescence Entries for CD34

Cell Types
Dental pulp stem
Cell Lines
Primary cell
Cancer Cell?
No
Method
Mutation
Type of senescence
Unclear
Senescence Effect
Induces
Primary Reference
Pisciotta et al. (2016) Human dental pulp stem cells (hDPSCs): isolation, enrichment and comparative differentiation of two sub-populations. BMC Dev Biol 15(2)14 (PubMed)

CD34 Gene Information

HGNC symbol
CD34 
Aliases
 
Common name
CD34 molecule 
Entrez Id
947
Description
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

CD34 Ontologies

Gene Ontology
Process: GO:7155; cell adhesion
GO:7165; signal transduction
GO:10629; negative regulation of gene expression
GO:10628; positive regulation of gene expression
GO:32733; positive regulation of interleukin-10 production
GO:71425; hematopoietic stem cell proliferation
GO:7160; cell-matrix adhesion
GO:8217; regulation of blood pressure
GO:32720; negative regulation of tumor necrosis factor production
GO:71636; positive regulation of transforming growth factor beta production
GO:30097; hemopoiesis
And 27 more GO terms
Cellular component: GO:5737; cytoplasm
GO:16020; membrane
GO:16021; integral component of membrane
GO:5886; plasma membrane
GO:16324; apical plasma membrane
GO:5764; lysosome
GO:48471; perinuclear region of cytoplasm
GO:5887; integral component of plasma membrane
GO:45171; intercellular bridge
GO:9925; basal plasma membrane
GO:9897; external side of plasma membrane
And 6 more GO terms
Function: GO:5515; protein binding
GO:61629; RNA polymerase II-specific DNA-binding transcription factor binding
GO:30246; carbohydrate binding
GO:43199; sulfate binding
Show all GO terms

Homologs of CD34 in Model Organisms

Mus musculus
Cd34
Rattus norvegicus
Cd34

External links

OMIM
142230
Ensembl
ENSG00000174059
Entrez Gene
947
UniGene
374990
1000 Genomes
1000 Genomes
HPRD
GenAtlas
CD34
GeneCards
CD34