Cell Senescence Entries for CKAP2

Cell Types
Mammary fibroblast
Cell Lines
Primary cell
Cancer Cell?
No
Method
Knockdown
Type of senescence
Unclear
Senescence Effect
Inhibits
Primary Reference
Avelar et al. (2021) A multidimensional systems biology analysis of cellular senescence in aging and disease. Genome Biol 21(1)91 (PubMed)

CKAP2 Gene Information

HGNC symbol
CKAP2 
Aliases
FLJ10749; LB1; se20-10; TMAP 
Common name
cytoskeleton associated protein 2 
Entrez Id
26586
Description
This gene encodes a cytoskeleton-associated protein that stabalizes microtubules and plays a role in the regulation of cell division. The encoded protein is itself regulated through phosphorylation at multiple serine and threonine residues. There is a pseudogene of this gene on chromosome 14. Alternative splicing results in multiple transcript variations. [provided by RefSeq, Nov 2013].

CKAP2 Ontologies

Gene Ontology
Process: GO:7049; cell cycle
GO:6915; apoptotic process
GO:7026; negative regulation of microtubule depolymerization
GO:45944; positive regulation of transcription by RNA polymerase II
GO:281; mitotic cytokinesis
Cellular component: GO:5737; cytoplasm
GO:5856; cytoskeleton
GO:5813; centrosome
GO:15630; microtubule cytoskeleton
GO:5874; microtubule
GO:72686; mitotic spindle
GO:5819; spindle
GO:922; spindle pole
Function:
Show all GO terms

Homologs of CKAP2 in Model Organisms

Danio rerio
si:ch211-266i6.3
Mus musculus
Ckap2
Rattus norvegicus
uncharacterized_F1LW

In other databases

CellAge gene expression
  • This gene is present as CKAP2

External links

OMIM
611569
Ensembl
ENSG00000136108
Entrez Gene
26586
UniGene
594461
1000 Genomes
1000 Genomes
HPRD
GenAtlas
CKAP2
GeneCards
CKAP2