Cell Senescence Entries for ESRRB

Cell Types
Glioblastoma
Cell Lines
A172
Cancer Cell?
Yes
Method
Knockdown
Type of senescence
Stress-induced
Senescence Effect
Induces
Primary Reference
Heckler et al. (2015) ERRβ splice variants differentially regulate cell cycle progression. Cell Cycle 14(1)31-45 (PubMed)

ESRRB Gene Information

HGNC symbol
ESRRB 
Aliases
DFNB35; ERR2; ERRb; ERRbeta; ESRL2; NR3B2 
Common name
estrogen related receptor beta 
Entrez Id
2103
Description
This gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development. [provided by RefSeq, Jul 2008].

ESRRB Ontologies

Gene Ontology
Process: GO:6355; regulation of transcription, DNA-templated
GO:43401; steroid hormone mediated signaling pathway
GO:6367; transcription initiation from RNA polymerase II promoter
GO:30522; intracellular receptor signaling pathway
GO:45893; positive regulation of transcription, DNA-templated
GO:6357; regulation of transcription by RNA polymerase II
GO:45944; positive regulation of transcription by RNA polymerase II
GO:45494; photoreceptor cell maintenance
GO:8283; cell population proliferation
GO:19827; stem cell population maintenance
GO:71931; positive regulation of transcription involved in G1/S transition of mitotic cell cycle
And 8 more GO terms
Cellular component: GO:5634; nucleus
GO:5654; nucleoplasm
GO:5829; cytosol
GO:5737; cytoplasm
GO:5694; chromosome
GO:793; condensed chromosome
GO:785; chromatin
GO:32039; integrator complex
Function: GO:8270; zinc ion binding
GO:46872; metal ion binding
GO:3677; DNA binding
GO:3700; DNA-binding transcription factor activity
GO:43565; sequence-specific DNA binding
GO:5496; steroid binding
GO:3707; steroid hormone receptor activity
GO:981; DNA-binding transcription factor activity, RNA polymerase II-specific
GO:5515; protein binding
GO:978; RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:4879; nuclear receptor activity
And 6 more GO terms
Show all GO terms

Homologs of ESRRB in Model Organisms

Danio rerio
esrrb
Mus musculus
Esrrb
Rattus norvegicus
Esrrb

External links

OMIM
602167
Ensembl
ENSG00000119715
Entrez Gene
2103
UniGene
435845
1000 Genomes
1000 Genomes
HPRD
GenAtlas
ESRRB
GeneCards
ESRRB