Cell Senescence Entries for HJURP

Cell Types
Dermal fibroblast, Umbilical vein endothelial
Cell Lines
Primary cell
Cancer Cell?
No
Method
Knockdown, Overexpression
Type of senescence
Unclear
Senescence Effect
Inhibits
Primary Reference
Heo et al. (2013) HJURP regulates cellular senescence in human fibroblasts and endothelial cells via a p53-dependent pathway. J Gerontol A Biol Sci Med Sci 68(8)914-25 (PubMed)

HJURP Gene Information

HGNC symbol
HJURP 
Aliases
DKFZp762E1312; FAKTS; hFLEG1; URLC9 
Common name
Holliday junction recognition protein 
Entrez Id
55355
Description

HJURP Ontologies

Gene Ontology
Process: GO:7049; cell cycle
GO:7059; chromosome segregation
GO:43254; regulation of protein-containing complex assembly
GO:34080; CENP-A containing nucleosome assembly
GO:51101; regulation of DNA binding
Cellular component: GO:5634; nucleus
GO:5654; nucleoplasm
GO:5730; nucleolus
GO:5739; mitochondrion
GO:5694; chromosome
GO:775; chromosome, centromeric region
GO:776; kinetochore
GO:43229; intracellular organelle
Function: GO:3677; DNA binding
GO:5515; protein binding
GO:42393; histone binding
GO:42802; identical protein binding
Show all GO terms

Homologs of HJURP in Model Organisms

Mus musculus
Hjurp
Rattus norvegicus
Hjurp

In other databases

CellAge gene expression
  • This gene is present as HJURP

External links

OMIM
612667
Ensembl
ENSG00000123485
Entrez Gene
55355
UniGene
532968
1000 Genomes
1000 Genomes
HPRD
GenAtlas
HJURP
GeneCards
HJURP