Cell Senescence Entries for KIFC1

Cell Types
Lung fibroblast
Cell Lines
IMR-90
Cancer Cell?
No
Method
Knockdown
Type of senescence
Unclear
Senescence Effect
Inhibits
Primary Reference
Kim et al. (2013) KIFC1 is essential for bipolar spindle formation and genomic stability in the primary human fibroblast IMR-90 cell. Cell Struct Funct 38(1)21-30 (PubMed)

KIFC1 Gene Information

HGNC symbol
KIFC1 
Aliases
HSET; KNSL2 
Common name
kinesin family member C1 
Entrez Id
3833
Description

KIFC1 Ontologies

Gene Ontology
Process: GO:7049; cell cycle
GO:51301; cell division
GO:7018; microtubule-based movement
GO:90307; mitotic spindle assembly
GO:7080; mitotic metaphase plate congression
GO:70; mitotic sister chromatid segregation
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:16020; membrane
GO:5768; endosome
GO:5856; cytoskeleton
GO:5874; microtubule
GO:5769; early endosome
GO:5815; microtubule organizing center
GO:5819; spindle
GO:72686; mitotic spindle
GO:5871; kinesin complex
And 1 more GO terms
Function: GO:166; nucleotide binding
GO:5524; ATP binding
GO:3774; cytoskeletal motor activity
GO:8017; microtubule binding
GO:3777; microtubule motor activity
GO:16887; ATP hydrolysis activity
Show all GO terms

Homologs of KIFC1 in Model Organisms

Caenorhabditis elegans
klp-3
Danio rerio
kifc1
Drosophila melanogaster
ncd
Mus musculus
Kifc5b
Rattus norvegicus
Kifc1
Saccharomyces cerevisiae
KAR3
Schizosaccharomyces pombe
klp1

In other databases

GenAge model organism genes
  • A homolog of this gene for Saccharomyces cerevisiae is present as KAR3
CellAge gene expression
  • This gene is present as KIFC1

External links

OMIM
603763
Ensembl
ENSG00000056678
Entrez Gene
3833
UniGene
436912
1000 Genomes
1000 Genomes
HPRD
GenAtlas
KIFC1
GeneCards
KIFC1