Cell Senescence Entries for NINJ1
- Cell Types
- Liver cancer
- Cell Lines
- Huh7
- Cancer Cell?
- Yes
- Method
- Overexpression
- Type of senescence
- Unclear
- Senescence Effect
- Induces
- Primary Reference
- Toyama et al. (2005) Ninjurin1 increases p21 expression and induces cellular senescence in human hepatoma cells. J Hepatol 41(4)637-43 (PubMed)
NINJ1 Gene Information
- HGNC symbol
- NINJ1
- Aliases
- NIN1
- Common name
- ninjurin 1
- Entrez Id
- 4814
- Description
- The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009].
NINJ1 Ontologies
- Gene Ontology
-
Process: GO:7155; cell adhesion
GO:12501; programmed cell death
GO:6954; inflammatory response
GO:1525; angiogenesis
GO:19835; cytolysis
GO:42246; tissue regeneration
GO:51260; protein homooligomerization
GO:50729; positive regulation of inflammatory response
GO:7399; nervous system development
GO:45766; positive regulation of angiogenesis
GO:2232; leukocyte chemotaxis involved in inflammatory response
And 5 more GO terms Cellular component: GO:16020; membrane
GO:16021; integral component of membrane
GO:5886; plasma membrane
GO:5576; extracellular region
GO:30054; cell junction
GO:45202; synapse
GO:97060; synaptic membrane
Show all GO termsFunction: GO:5515; protein binding
GO:1530; lipopolysaccharide binding
GO:98631; cell adhesion mediator activity
Homologs of NINJ1 in Model Organisms
- Danio rerio
- LOC100150223
- Drosophila melanogaster
- NijC
- Mus musculus
- Ninj1
- Rattus norvegicus
- Ninj1
External links
- OMIM
- 602062
- Ensembl
- ENSG00000131669
- Entrez Gene
- 4814
- UniGene
- 494457
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- NINJ1
- GeneCards
- NINJ1