Cell Senescence Entries for NLK
- Cell Types
- Colon cancer
- Cell Lines
- HCT116
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Mendes-Pereira et al. (2014) NLK is a novel therapeutic target for PTEN deficient tumour cells. PLoS One 7(10)e47249 (PubMed)
NLK Gene Information
- HGNC symbol
- NLK
- Aliases
- Common name
- nemo like kinase
- Entrez Id
- 51701
- Description
NLK Ontologies
- Gene Ontology
-
Process: GO:6468; protein phosphorylation
GO:16310; phosphorylation
GO:165; MAPK cascade
GO:6355; regulation of transcription, DNA-templated
GO:18107; peptidyl-threonine phosphorylation
GO:30178; negative regulation of Wnt signaling pathway
GO:35556; intracellular signal transduction
GO:42501; serine phosphorylation of STAT protein
GO:46777; protein autophosphorylation
GO:16055; Wnt signaling pathway
GO:50821; protein stabilization
And 3 more GO terms Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:43231; intracellular membrane-bounded organelle
GO:5654; nucleoplasm
GO:5829; cytosol
Show all GO termsFunction: GO:46872; metal ion binding
GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:287; magnesium ion binding
GO:4707; MAP kinase activity
And 5 more GO terms
Homologs of NLK in Model Organisms
- Caenorhabditis elegans
- lit-1
- Danio rerio
- nlk2
- Drosophila melanogaster
- nmo
- Mus musculus
- Nlk
- Rattus norvegicus
- Nlk
External links
- OMIM
- 609476
- Ensembl
- ENSG00000087095
- Entrez Gene
- 51701
- UniGene
- 208759
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- NLK
- GeneCards
- NLK