Cell Senescence Entries for PI4KB
- Cell Types
- Lung fibroblast
- Cell Lines
- IMR-90
- Cancer Cell?
- No
- Method
- Knockdown
- Type of senescence
- Oncogene-induced
- Senescence Effect
- Induces
- Primary Reference
- Su et al. (2019) The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response. J Cell Sci 131(6)117-26 (PubMed)
PI4KB Gene Information
- HGNC symbol
- PI4KB
- Aliases
- PI4K-BETA; pi4K92; PIK4CB
- Common name
- phosphatidylinositol 4-kinase beta
- Entrez Id
- 5298
- Description
PI4KB Ontologies
- Gene Ontology
-
Process: GO:16310; phosphorylation
GO:6629; lipid metabolic process
GO:46854; phosphatidylinositol phosphate biosynthetic process
GO:48015; phosphatidylinositol-mediated signaling
GO:7165; signal transduction
GO:6661; phosphatidylinositol biosynthetic process
GO:6898; receptor-mediated endocytosis
GO:7040; lysosome organization
GO:44238; primary metabolic process
Cellular component: GO:5737; cytoplasm
GO:16020; membrane
GO:5794; Golgi apparatus
GO:5783; endoplasmic reticulum
GO:5739; mitochondrion
GO:5741; mitochondrial outer membrane
GO:139; Golgi membrane
GO:12505; endomembrane system
GO:48471; perinuclear region of cytoplasm
GO:30867; rough endoplasmic reticulum membrane
GO:5829; cytosol
And 2 more GO terms
Show all GO termsFunction: GO:166; nucleotide binding
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:5515; protein binding
GO:4430; 1-phosphatidylinositol 4-kinase activity
GO:52742; phosphatidylinositol kinase activity
GO:71889; 14-3-3 protein binding
Homologs of PI4KB in Model Organisms
- Caenorhabditis elegans
- pifk-1
- Danio rerio
- pi4kb
- Mus musculus
- Pi4kb
- Rattus norvegicus
- Pi4kb
- Saccharomyces cerevisiae
- PIK1
- Schizosaccharomyces pombe
- pik1
External links
- OMIM
- 602758
- Ensembl
- ENSG00000143393
- Entrez Gene
- 5298
- UniGene
- 632465
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- PI4KB
- GeneCards
- PI4KB