Cell Senescence Entries for RPS9

Cell Types
Osteosarcoma
Cell Lines
U2OS
Cancer Cell?
Yes
Method
Knockdown
Type of senescence
Unclear
Senescence Effect
Inhibits
Primary Reference
Lindström et al. (2011) Silencing of ribosomal protein S9 elicits a multitude of cellular responses inhibiting the growth of cancer cells subsequent to p53 activation. PLoS One 5(3)e9578 (PubMed)

RPS9 Gene Information

HGNC symbol
RPS9 
Aliases
S9 
Common name
ribosomal protein S9 
Entrez Id
6203
Description
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S4P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. [provided by RefSeq, Jul 2008].

RPS9 Ontologies

Gene Ontology
Process: GO:6412; translation
GO:8284; positive regulation of cell population proliferation
GO:2181; cytoplasmic translation
GO:45903; positive regulation of translational fidelity
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:16020; membrane
GO:110165; cellular anatomical entity
GO:5840; ribosome
GO:5925; focal adhesion
GO:5730; nucleolus
GO:15935; small ribosomal subunit
GO:1990904; ribonucleoprotein complex
GO:22627; cytosolic small ribosomal subunit
GO:5654; nucleoplasm
And 5 more GO terms
Function: GO:3723; RNA binding
GO:3735; structural constituent of ribosome
GO:5515; protein binding
GO:19843; rRNA binding
GO:45182; translation regulator activity
Show all GO terms

Homologs of RPS9 in Model Organisms

Caenorhabditis elegans
rps-9
Danio rerio
rps9
Drosophila melanogaster
RpS9
Mus musculus
Rps9
Rattus norvegicus
Rps9
Saccharomyces cerevisiae
RPS9A
Schizosaccharomyces pombe
rps9a

In other databases

CellAge gene expression
  • This gene is present as RPS9

External links

OMIM
603631
Ensembl
ENSG00000170889
Entrez Gene
6203
UniGene
546288
1000 Genomes
1000 Genomes
HPRD
GenAtlas
RPS9
GeneCards
RPS9